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Mechanisms of Lymphocyte Activation and Immune Regulation XI

Advances in Experimental Medicine and Biology 596, Advances in Experimental Medicine and Biology 596

Erschienen am 06.02.2007, 1. Auflage 2007
Bibliografische Daten
ISBN/EAN: 9780387465272
Sprache: Englisch
Umfang: x, 198 S., 44 s/w Illustr., 198 p. 44 illus.
Einband: gebundenes Buch

Beschreibung

InhaltsangabeRegulation and Function of the E2A Proteins in B Cell Development.- Multiple Roles for Blimp-1 in B and T Lymphocytes.- Memory B Cell Evolution: B Cell Biology.- BCR-linked Factors in Developmental Fate Decisions.- Gene Regulatory Networks that Orchestrate the Development of B Lymphocyte Precursors.- Rules for the Rearrangement Events at the L Chain Gene Loci of the Mouse.- Regulation of AID Function In Vivo.- Targeting of AID to Immunoglobulin Genes.- Targeting AID to the Ig Genes.- DNA Replication to Aid Somatic Hypermutation.- Regulation of Activation Induced Deaminase via Phosphorylation.- Modulation of MHC Class II Signal Transduction by CD19.- Role of NFUP?B Signaling in Normal and Malignant B Cell Development.- Fc Receptor-like Proteins (FCRL): Immunomodulators of B Cell Function.- Tolerance Mechanisms in the Late Phase of the Antibody Response.- Role of RS/?DE in B Cell Receptor Editing.- The Regulation of Receptor Editing.- B Cell Hyporesponsiveness and Autoimmunity: A New Paradigm.

Autorenportrait

InhaltsangabeRegulation and Function of the E2A Proteins in B Cell Development.- Multiple Roles for Blimp-1 in B and T Lymphocytes.- Memory B Cell Evolution: B Cell Biology.- BCR-linked Factors in Developmental Fate Decisions.- Gene Regulatory Networks that Orchestrate the Development of B Lymphocyte Precursors.- Rules for the Rearrangement Events at the L Chain Gene Loci of the Mouse.- Regulation of AID Function In Vivo.- Targeting of AID to Immunoglobulin Genes.- Targeting AID to the Ig Genes.- DNA Replication to Aid Somatic Hypermutation.- Regulation of Activation Induced Deaminase via Phosphorylation.- Modulation of MHC Class II Signal Transduction by CD19.- Role of NFUP?B Signaling in Normal and Malignant B Cell Development.- Fc Receptor-like Proteins (FCRL): Immunomodulators of B Cell Function.- Tolerance Mechanisms in the Late Phase of the Antibody Response.- Role of RS/?DE in B Cell Receptor Editing.- The Regulation of Receptor Editing.- B Cell Hyporesponsiveness and Autoimmunity: A New Paradigm.